Figure 1 | Cell Death & Disease

Figure 1

From: DED or alive: assembly and regulation of the death effector domain complexes

Figure 1

Schematic representations of the structures of DED proteins (ribbon format with transparent solvent-accessible surface area) along with their complete linear domain organisation. Protein structures: (a) Homology model of human FLIP DEDs48 (b) NMR solution structure of FADD DED (PDB ID: 2GF5) 7 (c) NMR solution structure of PEA-15 DED (PDB ID: 2LS7)191 (d) Homology model of procaspase-8 DEDs48 (e) Homology model of procaspase-10 DEDs generated using the I-TASSER web server192

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