Figure 5

ER stress induction promotes CXCL10 expression. Primary retinal ganglion cells were isolated and treated with 2 μg/ml of tunicamycin for 24 h. The mRNA levels of ER stress target genes (GRP78, CHOP, and Xbp1s) (a–c), CXCL10 (d), and CXCR3 (e) were quantified by qPCR. *P<0.05 compared with control. N=4