Figure 6 | Cell Death & Disease

Figure 6

From: Endoplasmic reticulum stress-regulated CXCR3 pathway mediates inflammation and neuronal injury in acute glaucoma

Figure 6

CXCR3 deletion attenuates ER stress-induced retinal cell apoptosis. WT and CXCR3 ko mice were intravitreally injected with tunicamycin (1 μg/eye) and retinas were collected at 24 h after injection. (a–d) qPCR was performed to measure the mRNA expression of CXCL10 and ER stress markers GRP78, CHOP, Xbp1s. (e) Apoptosis was analyzed by detecting histone-associated DNA fragmentation. *P<0.05 compared with tunicamycin-injected WT. N=3

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