Figure 4 | Cell Death & Disease

Figure 4

From: Genetic ablation of homeodomain-interacting protein kinase 2 selectively induces apoptosis of cerebellar Purkinje cells during adulthood and generates an ataxic-like phenotype

Figure 4

The absence of HIPK2 induces an activation of pro-apoptotic pathways. Confocal images of cerebellar cortex sections from wild-type (a–c, g–i, and m–o) and Hipk2−/− mice (d–f, j–l, and p–r) performed with antibodies against BAX (b and e), BCL-2 (h and k), BCL-XL (n and q), and calbindin (a–p), and merged images (c–r). Scale bar, 20 μm. All pictures were taken in the same conditions

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