Table 2 A list of DAMP molecules possibly associated with necrotic or/and necroptotic cells

From: Role of necroptosis in the pathogenesis of solid organ injury

Ligand

Receptor

HMGB-1

RAGE, TLR-2, -4 and -9101, 102

Histone

TLR-2 and -4103, 104

ATP

P2X, P2Y105

HSP

CD24106, 107

DNA

TLR-9108

ECM components, e.g. fibronectin, fibrinogen, hyaluronan and biglycan

TLRs, CD44107, 109

IL-33

ST2L/IL1RAcP34, 110

Cyclophilin A

CD147111, 112

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