Figure 4
From: Loss of serum response factor induces microRNA-mediated apoptosis in intestinal smooth muscle cells
Identification of dysregulated miRNAs in the KO smooth muscle. MiRNA-seq analysis of KO upper and lower jejunum along with WT controls identified 892 miRNAs. After filtering by expression levels, 519 miRNAs were used for further analysis. (a) Expression profile of miRNAs identified in WT and KO smooth muscle. (b) Number of dysregulated miRNAs. (c) Comparison of total dysregulated miRNAs between WT and KO. (d) Pathway analysis of SRF-dependent miRNAs. Interactions between upregulated miRNAs and SRF were analyzed using IPA software
