Figure 1

Cellular prion protein (PrPc) ameliorates post-ischemic neurological impairment. (a) Tight rope, (b) rota rod, (c) corner turn and (d) balance beam test in wild type (WT), PrPc knockout (PrP−/−) and PrPc overexpressing (PrP+/+) mice exposed to 45 min of MCA occlusion followed by 28 days reperfusion. *Significantly different from WT mice, P<0.05. #Significantly different from PrP−/− or PrP+/+ mice, P<0.05