Figure 2 | Cell Death & Disease

Figure 2

From: Plasma membrane poration by opioid neuropeptides: a possible mechanism of pathological signal transduction

Figure 2

Big Dyn induces fluctuations in the plasma membrane conductance of DRG neurons. (a, top) Representative transmembrane holding current induced by 1 μM Big Dyn observed in ~85% of tested neurons. (a, bottom) Application of Big Dyn resulted in the appearance of current surges strongly varying in duration and amplitude (note the different time scales). (b and c) Alternative dynamical behavior observed in about ~15% of cells. All measurements were conducted on DRG neurons clamped at −100 mV

Back to article page