Figure 1 | Cell Death & Disease

Figure 1

From: Hemoglobinuria-related acute kidney injury is driven by intrarenal oxidative reactions triggering a heme toxicity response

Figure 1

Renal outcome of blood transfusion-related hemolysis in guinea pigs. (a) Macroscopic view of kidneys of new blood-transfused and old blood-transfused guinea pigs at 24 h after treatment. (b) Hematoxylin and eosin-stained kidney sections of new blood-transfused, old blood-transfused, and old blood-transfused, haptoglobin (Hp)-treated animals at 24 h after treatment. (c) Renal tissue expression of lipocalin 2 (LCN2)/neutrophil gelatinase-associated lipocalin (NGAL) mRNA at 24 h after treatment (*P<0.01)

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