Table 1 The main plasma miRNAs with obvious differentiation in expression between HCC patients with family history and healthy volunteer based on MiRNABASE16.0 microarray result

From: MiR-216b is involved in pathogenesis and progression of hepatocellular carcinoma through HBx-miR-216b-IGF2BP2 signaling pathway

MiRNA name

Patient 1

Patient 2

Patient 3

Healthy volunteer

Fold change

Chr

hsa-miR-215

4.133392

5.489004

5.329173

−3.01875

277.3476

chr1

hsa-miR-3188

3.99423

3.776789

4.041749

−3.01875

124.5749

chr19

hsa-miR-374a

5.024302

3.531907

−0.24684

−3.01875

121.4428

chrX

hsa-miR-23b

1.58499

3.752035

4.434753

−3.01875

102.9296

chr9

hsa-miR-18a

4.085276

3.931359

1.920744

−3.01875

97.30162

chr13

hsa-miR-4271

1.936976

3.99423

4.005849

−3.01875

96.79688

chr3

hsa-miR-1471

3.859828

2.288063

4.021979

−3.01875

96.30528

chr2

hsa-miR-320a

4.005849

2.026072

3.648332

−3.01875

88.27788

chr8

hsa-miR-188-5p

1.506212

2.23718

4.513003

−3.01875

82.09368

chrX

hsa-miR-1183

3.648332

3.700071

2.258003

−3.01875

81.90769

chr7

hsa-miR-3610

−0.02192

1.58499

4.322987

−3.01875

64.8362

chr8

hsa-miR-199a-3p

2.161674

3.913376

2.009884

−3.01875

63.6739

chr1

hsa-miR-454

4.279344

1.842776

−1.78566

−3.01875

62.93342

chr17

hsa-miR-423-5p

3.752035

2.258003

2.23718

−3.01875

62.05822

chr17

hsa-miR-151-5p

3.931359

2.142199

1.58499

−3.01875

61.2467

chr8

hsa-miR-324-3p

3.776789

1.705998

0.076838

−3.01875

48.69201

chr17

hsa-miR-140-5p

2.310577

2.318683

2.060964

−3.01875

38.15187

chr16

hsa-miR-130b

2.026072

1.952285

2.310577

−3.01875

34.85976

chr22

hsa-miR-197

2.288063

1.910013

1.952285

−3.01875

33.80174

chr1

hsa-miR-148b

2.142199

2.161674

1.795104

−3.01875

33.38865

chr12

hsa-miR-30a

1.60829

1.803955

2.318683

−3.01875

31.14729

chr6

hsa-miR-484

1.892021

1.742625

1.936976

−3.01875

29.41176

chr16

hsa-miR-7

1.705998

1.671912

1.387086

−3.01875

24.48793

chr9

hsa-miR-30c

1.920744

2.088509

−0.02192

−3.01875

24.37926

chr1

hsa-miR-194

0.076838

2.009884

1.653321

−3.01875

22.22771

chr1

hsa-miR-222

1.478218

1.653321

−1.68234

−3.01875

16.86627

chrX

hsa-miR-486-3p

1.300588

1.318576

−1.61597

−3.01875

14.27426

chr8

hsa-miR-221

−0.01614

1.631837

−1.60126

−3.01875

11.93418

chrX

hsa-miR-122

5.884915

8.985012

9.239693

6.08211

5.75829

chr18

hsa-miR-1290

4.739727

5.991765

8.465335

5.489004

3.293882

chr1

hsa-miR-1228

1.910013

4.021979

1.506212

4.677724

0.297525

chr12

hsa-miR-1234

−3.22914

3.488344

−1.54977

3.913376

0.25819

chr8

hsa-miR-18b

2.318683

1.892021

0.042057

3.700071

0.249548

chrX

hsa-miR-126*

2.329368

2.310577

1.631837

4.322987

0.217936

chr9

hsa-miR-191*

−3.22914

1.237284

−1.58659

4.133392

0.053127

chr3

hsa-miR-138-2*

−3.22914

−3.18149

−3.32196

3.488344

0.009411

chr16

hsa-miR-216b

−3.22914

−3.18149

−3.32196

3.752035

0.007839

chr2

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