Table 2 Correlation of miR-216b expression in HCC with 50 patients’ clinical and pathological properties

From: MiR-216b is involved in pathogenesis and progression of hepatocellular carcinoma through HBx-miR-216b-IGF2BP2 signaling pathway

Parameters

Low miR-216b expression (N=90)

High miR-216b expression (N=60)

χ 2 -Test

Gender

Male (42)-46.7%

Male (24)-40%

P=0.861

 

Female (48)-53.3%

Female (36)-60%

 

Age

≥60 (57)-63.3%

≥60 (24)-40%

P=0.183

 

<60 (33)-36.7%

<60 (36)-60%

 

Tumor size

≥5 cm (42)-46.7%

≥5 cm (9)-15%

P=0.044*

 

<5 cm (48)-53.3%

<5 cm (51)-85%

 

Hepatitis infection

Infected (72)-80%

Infected (30)-50%

P=0.026*

 

Not infected (18)-20%

Not infected (30)-50%

 

HBV DNA quantity differentiation

≥1000 (63)-70%

≥1000 (9)-15%

P=0.001*

 

<1000 (27)-30%

<1000 (51)-85%

 
 

High/moderate (60)-66.7%

High/moderate (48)-80%

P=0.479

 

Low (30)-33.3%

Low (12)-20%

 

Cirrhosis

Present (36)-40%

Present (18)-30%

P=0.674

 

Absent (54)-60%

Absent (42)-70%

 

PVTT

Present (45)-50%

Present (12)-30%

P=0.032*

 

Absent (45)-50%

Absent (48)-70%

 

AFP level>200 ug/l

Yes (33)-36.7%

Yes (15)-25%

P=0.578

 

No (57)-63.3%

No (45)-75%

 

Child–Pugh score

A (81)-90%

A (57)-95%

P=0.741

 

B (9)-10%

B (3)-5%

 
  1. Abbreviations: AFP, alpha-fetoprotein; PVTT, portal vein tumor thrombosis. *Means P<0.05