Table 3 Independent prognostic factors of OS and DFS for HCC patients by multivariate analyses

From: Prognostic significance of Cbx4 expression and its beneficial effect for transarterial chemoembolization in hepatocellular carcinoma

Variables

Overall survival

Disease-free survival

 

HR (95% CI)

P -value

HR (95% CI)

P -value

Gender (female versus male)

1.003 (0.711–1.415)

0.986

1.039 (0.639–1.688)

0.878

Race (minority versus han)

1.054 (0.835–1.330)

0.657

0.864 (0.617–1.210)

0.395

HBsAg (negative versus positive)

0.884 (0.629–1.242)

0.477

0.878 (0.546–1.412)

0.592

Anti-HCV (negative versus positive)

1.047 (0.142–7.705)

0.964

0.604 (0.080–4.557)

0.625

Hepatocirrhosis (no versus yes)

0.957 (0.740–1.238)

0.738

0.798 (0.549–1.161)

0.238

Smoking (no versus yes)

1.354 (0.927–1.979)

0.117

0.981 (0.590–1.631)

0.941

Drinking (no versus yes)

0.702 (0.478–1.031)

0.071

1.031 (0.600–1.771)

0.912

AFP (≥25 versus <25 ng/ml)

1.017 (0.810–1.276)

0.885

0.730 (0.532–1.000)

0.050

MVD (>50 versus ≤50)

1.287 (0.985–1.682)

0.064

1.215 (0.838–1.762)

0.305

Tumor number (single versus multiple)

0.948 (0.724–1.240)

0.694

1.148 (0.783–1.681)

0.480

TNM stage (I–II versus III versus IV)

1.138 (0.911–1.420)

0.255

1.007 (0.740–1.371)

0.962

Tumor size (≥5 versus <5 cm)

1.875 (1.382–2.545)

5.4 × 10−5

1.244 (0.848–1.825)

0.263

Histological grading (high versus low)

1.588 (1.256–2.008)

1.1 × 10−4

1.432 (1.034–1.983)

0.031

Cbx4 (high versus low)

1.705 (1.301–2.233)

1.0 × 10−4

1.493 (1.027–2.170)

0.036

  1. Abbreviations: CI, confidence interval; HR, hazards ratio
  2. Multivariate analysis was performed using the Cox multivariate proportional hazards regression model with stepwise manner (forward, likelihood ratio)
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