Figure 3
From: Antitumour potential of BPT: a dual inhibitor of cdk4 and tubulin polymerization

A549 and LS174T cells were analysed by western blot technique. The treatment of p53+ cells (A549 and LS174T) with BPT at IC50 concentration for 24 h resulted in induction of p53, p21CIP1/WAF1 (p21) and p27KIP1 (p27), whereas cyclin B1 and Cdk1 levels were downregulated