Figure 3 | Cell Death & Disease

Figure 3

From: Mitofusin-mediated ER stress triggers neurodegeneration in pink1/parkin models of Parkinson’s disease

Figure 3

Increase in mitochondria–ER contact points in PINK1 or PARKIN mutant fibroblasts. (a and b) Quantification of mitochondria–ER contacts in human fibroblasts (asterisks, chi-square two-tailed, 95% confidence intervals) (b), and representative electron microscopy images (a). Yellow asterisks show mitochondria in contact with ER (arrows). ER, endoplasmic reticulum; m, mitochondria. PINK1: c.261_276del16; p.T90LfsX12 (homozygous); PARKIN: deletion of exons 3 and 4 (homozygous)

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