Figure 7
Pharmacokinetic profiles and biodistributions. (a) Nude mice were administered an i.v. injection of sTR, FA1FT and HA5ST (1 nmol per mouse), and blood concentrations of the recombinant proteins were monitored by ELISA. Protein concentrations were calculated as a percent relative to the 2 min samples. Each data point represents the mean value (n=4). Statistical analysis was carried out with unpaired t-test, two-tailed test, **P<0.01. (b) Nude mice were administered an i.p. injection of sTR, FA1FT and HA5ST (5 nmol per mouse). Supernatants of tissue homogenates were analyzed at indicated time points post injection by ELISA. Protein concentrations were calculated as a percent relative to the 10 min samples. Each data point represents the mean value (n=3)
