Figure 3 | Cell Death & Disease

Figure 3

From: Does murine spermatogenesis require WNT signalling? A lesson from Gpr177 conditional knockout mouse models

Figure 3

Loss of Gpr177 blocked the extracellular secretion of WNT proteins. (a– c) Protein levels of WNT3 (a), WNT3A (b) and WNT7A (c) in germ cell culture supernatants from control, Gpr177flox/flox, Mvh-Cre; Gpr177flox/flox, Stra8-Cre and Gpr177flox/flox, Amh-Cre testes. (d–f) Secreted WNT4 (d), WNT6 (e) and WNT11 (f) examined by ELISA methods were observed in supernatants of Sertoli cells from control and three Gpr177 cKO testes. The data are expressed as the mean±S.E.M. **P<0.01

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