Figure 1 | Cell Death & Disease

Figure 1

From: Glucolipotoxicity initiates pancreatic β-cell death through TNFR5/CD40-mediated STAT1 and NF-κB activation

Figure 1

Effect of glucolipotoxicity on β-cell ontology. Comparative analysis of gene expression from INS-1 cells incubated for 72 h in RPMI-1640 media supplemented with or without 28 mM glucose, plus 200 μM oleic acid, and 200 μM palmitic acid. Data are compiled from six independent microarray analyses (three per experimental group). Reactome pathway analysis (http://www.reactome.org) identified 13 significant biological functions/pathways (P<0.05)

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