Figure 5 | Cell Death & Disease

Figure 5

From: MCL-1 is required throughout B-cell development and its loss sensitizes specific B-cell subsets to inhibition of BCL-2 or BCL-XL

Figure 5

Plasma cells that persist in the absence of TNF receptor BCMA remain sensitive to ABT-737. Absolute numbers of PC (CD138+B220lo) after ABT-737 treatment of lethally irradiated mice reconstituted with Bcma−/− BM, performed as in Figure 4. Data represent one experiment and six animals per group. **P⩽0.01 (Statistical significance was calculated between the groups using a Mann–Whitney test)

Back to article page