Figure 4

Dose- and time-dependent decrease of intracellular ATP level in U87 (a), IC (b) and LN229 (c) cells after exposure to JS-K for 48 and 72 h. ATP level increased after treatment with etoposide (10 μM) in U87 (a) and LN229 (c) and decreased by H2O2 (3 mM) after 4 h exposure in all three cell lines. Mean values±s.d. of three independent experiments are plotted. Asterisks (*P<0.05, **P<0.01, ***P<0.001) indicate significance between JS-K and untreated controls