Figure 8 | Cell Death & Disease

Figure 8

From: Kinsenoside screening with a microfluidic chip attenuates gouty arthritis through inactivating NF-κB signaling in macrophages and protecting endothelial cells

Figure 8

In vivo examination of anti-inflammatory effects of Kin against gouty arthritis. (A) Histological analyses of rat ankle joints injected with MSU crystals and corresponding drugs (a, magnification, × 100, × 200; b, magnification, × 400). Black arrows indicate MSU-affected blood vessels. (B) Histological analyses of stomach (a) and kidney (b) after rats received injection of MSU crystals and corresponding drugs (magnification, × 200). (C) Perimeter assessments of ankles of rats injected with MSU crystals and corresponding drugs. (D) The effects of Kin on nociceptive reactions caused by hot water (tail-flick response, a) and acetic acid (writhing response, b). The data are presented as the means±S.D. **P<0.05 compared with 0 μg/ml of Kin. #P<0.05 compared with control. All data were obtained from at least three independent experiments

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