Figure 6 | Cell Death & Disease

Figure 6

From: miR-150 exerts antileukemia activity in vitro and in vivo through regulating genes in multiple pathways

Figure 6

Validation of four of the targets by luciferase assays. Predicted interaction sites of miR-150 in the (a) EIF4B, (b) FOXO4, (c) PRKCA, and (d) TET3 3′-UTR mRNA, and their site-directed mutations were described above the illustrations. Luciferase activities were determined at 24 h by normalizing firefly to renilla luciferase activity, and expressed as mean values±S.D. from three independent experiments in triplicate. *P<0.05; **P<0.01; ***P<0.001; #, no significance

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