Figure 2

Stereological quantification of nigral dopaminergic neurons. Numbers of TH and Nissl-positive nigral neurons are shown for the three genotypes (Dat-Cre, Retlx/lx and DAT-Retlx/lx) 2 weeks post MPTP treatment (a) and 3 months after MPTP treatment (b) and control mice which instead received saline (NaCl) (a and b). For each mouse the numbers on the side with mock injection (inj), AAV5-EGFP injection (EGFP) or AAV5-GDNF (GDNF) and on the non-injected contralateral side (con) are shown (n=6 animals per group)