Figure 3 | Cell Death & Disease

Figure 3

From: Ret is essential to mediate GDNF’s neuroprotective and neuroregenerative effect in a Parkinson disease mouse model

Figure 3

Quantification of striatal dopaminergic fiber density. TH immunoreactivity of striatal tissue sections is shown in a for DAT-Cre mice (upper panel), Retlx/lx mice (middle panel) and DAT-Retlx/lx mice (lower panel) at 2 weeks after MPTP treatment (first two columns) and 3 months after MPTP treatment (last two columns), for the injected hemispheres (inj., columns 1 and 3) and the contralateral hemispheres (con, columns 2 and 4). The quantification of striatal TH fiber density is presented in (b) for 2 weeks, and in c for 3 months after MPTP application. Scale bar, 40 μm in (a) (n=6 animals per group)

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