Figure 4 | Cell Death & Disease

Figure 4

From: Ret is essential to mediate GDNF’s neuroprotective and neuroregenerative effect in a Parkinson disease mouse model

Figure 4

Quantification of striatal dopamine levels. Striatal dopamine levels assessed by HPLC are shown for control animals (NaCl), for animal receiving MPTP and AAV5-EGFP (MPTP+EGFP), and for animals receiving MPTP and AAV5-GDNF (MPTP+GDNF) for the vector injected (inj) and the contralateral hemisphere (con). Data are shown from the three genotypes (Dat-Cre, Retlx/lx mice and DAT-Retlx/lx) at 2 weeks (a) and at 3 months post MPTP treatment (b) (n=6 animals per group)

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