Figure 5 | Cell Death & Disease

Figure 5

From: ZNF32 contributes to the induction of multidrug resistance by regulating TGF-β receptor 2 signaling in lung adenocarcinoma

Figure 5

ZNF32 deficiency might exhibit synergistic effects with a TGF-βR inhibitor to augment the anti-tumor effect of drugs and improve patient survival in vivo. Twenty-nine days after the injection of A549 and PC9 cells into the mice, the tumor mass was obtained. (a) Volume and weight of the tumor. (b) Growth curve of the tumor. (c) These samples were sliced and stained with HE to measure the necrosis area. (d) When the mice died, the survival time of each group was recorded, and the Kaplan–Meier survival curves for each group were analyzed (n=10 per group; *P<0.05). NS, non-significant difference. Each column and bar represents the median±S.D. of three independent experiments. The photograph shows a representative result from three independent experiments

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