Figure 6 | Cell Death & Disease

Figure 6

From: Metformin protects against apoptosis and senescence in nucleus pulposus cells and ameliorates disc degeneration in vivo

Figure 6

Metformin treatment alleviates nucleus pulposus cells senescence under oxidative stress. (a–b) SA-β-gal staining assay was performed in nucleus pulposus cells as treated above (original magnification × 200, scale bar: 20 μm). (c–d) The protein expression of p-p53, P53, p21WAF1 and p16INKa in nucleus pulposus cells treated as above. The data in the figures represent the averages±S.D. Significant differences between the treatment and control groups are indicated as **P<0.01, *P<0.05, n=3

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