Figure 2 | Cell Death & Disease

Figure 2

From: Emerging roles of extracellular vesicles in neurodegenerative disorders: focus on HIV-associated neurological complications

Figure 2

HIV budding is mediated by the exosome/microvesicle biogenesis pathway. HIV budding (left) and exosome release (right) share similar pathways. HIV Gag binds the viral RNA and drags it into the cytoplasmic face of intracellular vesicles, then the virus particles bud into the MVB. Subsequently, the virus-containing vesicles traffic to and fuse with the cell membrane, resulting in the release of virus particles

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