Figure 4 | Cell Death & Disease

Figure 4

From: Emerging roles of extracellular vesicles in neurodegenerative disorders: focus on HIV-associated neurological complications

Figure 4

The exosome response to HIV infection. (a) Exosomes from HIV-infected cells contain various molecules including ADAM17, TNFα, Nef and so on. These molecules upon entering the recipient cells then induce the target cell activation, apoptosis and HIV susceptibility. (b) Exosomes released from CD8+ T cells contain an antiviral membrane-bound factor that inhibits HIV-1 transcription

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