Figure 1
From: Knockout of Ccr2 alleviates photoreceptor cell death in rodent retina exposed to chronic blue light
Effect of Ccr2 knockout on light-induced retinal dysfunction in mice. Stimulus flash intensity was selected from 0.0095 to 9.49 cds/m2 in ERG analysis. (a) Representative scotopic ERG records at the flash intensity of 3.00 cds/m2 after 3 months in the four groups. Quantification of (b) a-wave amplitude and (c) b-wave amplitude of WT Ctrl, Ccr2−/− Ctrl, WT+BLE, and Ccr2−/−+BLE mice after 1 month. Quantification of (d) a-wave amplitude and (e) b-wave amplitude of WT Ctrl, Ccr2−/− Ctrl, WT+BLE, and Ccr2−/−+BLE mice after 3 months. Data are shown as the mean±S.E.M., n=10. One-way analysis of variance followed by Tukey’s multiple comparison test. *P<0.05, **P<0.01, WT+BLE group compared with the other three groups
