Figure 7
From: Knockout of Ccr2 alleviates photoreceptor cell death in rodent retina exposed to chronic blue light
Ccr2 knockout reduced the secretion of IL-1β in blue light-induced retinopathy. IL-1β immunoactivity (red) was detected expressed in all groups. Cell nuclei (blue) were counterstained with DAPI. The fluorescent photomicrographs indicated that more IL-1β was found co-localized with NLRP3 (green) in WT+BLE mice retina after 1 month and 3 months compared with that in WT Ctrl and Ccr2−/−+BLE mice retinas after 3 months
