Figure 1
From: MicroRNA-494 inhibits breast cancer progression by directly targeting PAK1
Expression of miR-494 in breast cancer cell lines and specimens. (a) Quantitative real-time PCR analysis of miR-494 expression in MCF-10A and nine breast cancer cell lines. The fold changes of relative expression of miR-494 versus that of MCF-10A are represented in the vertical axis. Experiments were performed three times. (b) Comparison of miR-494 abundance in 24 paired tumor and adjacent non-tumor tissues. The relative expression of miR-494 normalized to the internal control U6 is shown (P=0.0296, independent test). (c) In situ hybridization of miR-494 in breast cancer TMA (50 paired tumor and adjacent non-tumor tissues). The right is static map. Data are presented as mean±S.D. The symbols ** and *** denote significant statistical difference of P<0.01 and P<0.001 respectively by a two-tailed Student’s t-test
