Figure 6 | Cell Death & Disease

Figure 6

From: Curcumin represses mouse 3T3-L1 cell adipogenic differentiation via inhibiting miR-17-5p and stimulating the Wnt signalling pathway effector Tcf7l2

Figure 6

Repressed 3T3-L1 differentiation with curcumin treatment is associated with reduced miR-17-5p and increased Tcf7l2. (a-h) qRT-PCR showed the results of indicated target gene in 3T3-L1 cells collected at indicated time intervals during the differentiation process. (i) Illustration of the regulatory network on curcumin-mediated repression of adipogenesis, involving miR-17-5p inhibition and Wnt signalling cascade activation. N> or =3 for panels (a–i); *P<0.05; **or ##P<0.01; ***P<0.001. * or **, when curcumin treated group was compared with the DM group. ##, when the DM group was compared with the UD group. UD, undifferentiated; CUR, curcumin; DM, differentiation medium only; miR-17, miR-17-5p

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