Figure 3
From: Lack of collagen XV is protective after ischemic stroke in mice
Lack of ColXV does not influence brain edema. (a) Brain edema was measured as a % of swelling by using the formula ((V ipsilateral hemisphere−V contralateral hemisphere)/V contralateral hemisphere)*100. Values plotted are mean±S.E.M. Kruskall–Wallis test: P>0.05. (b-c) Photomicrographs of aquaporin 4 (b) and corresponding immunoreactivity quantifications (c) in the peri-ischemic area of injured WT and ColXV KO mice thrombolysed or not with rtPA 20 min after thromboembolic (TE) stroke. Values plotted are mean±S.E.M. Kruskall–Wallis test: P>0.05; N=4–5 per group. PI, peri-ischemic area
