Figure 7
From: REP1 inhibits FOXO3-mediated apoptosis to promote cancer cell survival
REP1 inhibits nuclear trans-localization of FOXO3. HEK293 cells were transfected with RFP-FOXO3 together with empty vector (no), GFP-REP1 WT, or GFP-REP1 Mut. Confocal fluorescent microscopy was used to evaluate the subcellular distribution of FOXO3 and REP1. Representative pictures are shown in (a), and the experimental quantitation of subcellular localization of FOXO3 is shown in (b). Graph represents three independent experiments and error bars represent S.D. from the mean. **P<0.001
