Figure 6 | Cell Death & Disease

Figure 6

From: Drosophila caspase activity is required independently of apoptosis to produce active TNF/Eiger during nociceptive sensitization

Figure 6

Microarray and behavioral analysis reveals E(z) as a functional downstream target gene of TNF/Eiger signaling. (a) Schematic of isolation of nociceptive sensory neurons and microarray analysis. (b) Categories of genes that have clear human orthologs, and that are upregulated in nociceptive sensory neurons that overexpress TNF/Eiger. (c) Quantification of UV-induced thermal allodynia on the expression of UAS-E(z)RNAi transgenes in nociceptive sensory neurons. (d) Quantification of TNF/Eiger-induced thermal allodynia on the expression of UAS-E(z)RNAi transgenes in nociceptive sensory neurons

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