Figure 7
From: Tsc1 expression by dendritic cells is required to preserve T-cell homeostasis and response
Tsc1 inhibits DCs apoptosis via repressing the mTORC1 pathway. (a) The percentage of DCs in the spleen from the indicated mice (n=6). (b) Annexin V and PI staining of splenic DCs from the indicated mice (n=3). (c and d) Apoptosis of splenic DCs, 16āh after i.v. injection with RAPA (30āĪ¼g per mouse) or S6K inhibitor (50āĪ¼g per mouse) (n=3). All mice analyzed were 6 week old. *P<0.05, **P<0.01; error bars represent S.D.; all data are representative of at least three independent experiments
