Figure 5 | Cell Death & Disease

Figure 5

From: Downregulation of renal tubular Wnt/β-catenin signaling by Dickkopf-3 induces tubular cell death in proteinuric nephropathy

Figure 5

Expression and localization of β-catenin in kidney cortex of murine protein overloaded model at different end points. (a) Expression of β-catenin (n=6) in kidney cortical lysates of protein overloaded mice at 4 weeks and 8 weeks. Representative immunoblots are shown. (b) Immunohistochemical staining of tubular β-catenin (red-arrows) on the respective kidney tissues. Bar scale=200 μm. (c) Immunohistochemical stainings of aquaporin-1 (proximal tubule marker) and β-catenin on contiguous kidney sections. Bar scale=100 μm. Graphs were expressed in mean± S.D. *P<0.05; #P<0.05, ##P<0.01

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