Table 1 Urine and serum biochemistry data of UNX C57/BL6 murine receiving 10 mg/g BSA for 4 or 8 weeks

From: Downregulation of renal tubular Wnt/β-catenin signaling by Dickkopf-3 induces tubular cell death in proteinuric nephropathy

BSA injection period

1 Week

4 Weeks

8 Weeks

 

UNX

UNX+ BSA (10 mg/g)

UNX

UNX+ BSA (10 mg/g)

UNX

UNX+ BSA (10 mg/g)

UACR (μg/mg)

270.8±88.8a

15 677.3±5009.6a

102.7±16.2

1621.8±768.4a,b

112.9±8.7c

6341.2±1486.6b,c

BUN (mg/dl)

29.8±2.7

35.0±7.3c

29.3±1.6a

46.0±7.2a,c

29.3±1.9a

49.1±1.9a,c

  1. Abbreviations: BSA, bovine serum albumin; BUN, blood urea nitrogen; UACR, urine albumin-to-creatinine ratio; UNX, uninephrectomized
  2. UACR and BUN were measured for the experimental animals (n=6) and expressed in mean±S.D. a=P<0.0001; b=P<0.05; c=P<0.001
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