Figure 4 | Cell Death & Disease

Figure 4

From: ANP32B deficiency impairs proliferation and suppresses tumor progression by regulating AKT phosphorylation

Figure 4

Re-expression of ANP32B promotes breast cancer cell growth in vivo. MDA-231-D3H2LN cells infected with shNC/EV, sh32b/EV and sh32b/GFP-ANP32B were injected into right side of the mammary fat pad of the mice. (a) After 4 weeks, the tumor growth was monitored using bioluminescent imaging and the representative bioluminescent images (top)/total flux (bottom) are shown. Data are presented as mean± S.D. and symbol *indicates P<0.05 between lined groups. (b) The macroscopic appearances of tumors at 4 weeks after injection. (c) Representative images of immunohistochemical staining for Ki-67 of mammary tumors at 4 weeks after injection

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