Figure 5
ANP32B expression is elevated in breast cancer tumors and positive correlates with historical grade of breast cancers. (a) ANP32B expression was plotted using the immunohistochemical scores as described in the Material and Methods. ANP32B expression scores are shown as box plots, with the horizontal lines representing the median; the bottom and top of the boxes representing the 25th and 75th percentiles, respectively; and vertical bars representing the range of data. We compared breast cancer tumors with matched adjacent normal breast epithelium using the Mann–Whitney test, n=100. (b) Representative images from immunohistochemical staining of ANP32B from one pair of breast cancer and adjacent normal tissues. The scale bar represents 30 μm. (c) Expression of ANP32B in five pairs of clinical breast cancer specimens. N and T mean adjacent normal tissue and paired breast cancer tumor, respectively. (d) Box plots of ANP32B expression in breast cancers with different historical grades. Data were analyzed by one-way ANOVA test. (e) Representative images from immunohistochemical staining of ANP32B from three cases in different histological grades (1–3). The scale bar represents 30 μm
