Figure 5

Quantification of exogenous 3HK and KMO mRNA levels. (a) Plot showing 3HK concentration remaining in each cell and control incubation plotted against incubation time, n=4, the S.E.M. is indicated by error bars on the plot, data are representative of two independent experiments. (b) Table showing relative quantification of mRNA levels corresponding to each kynurenine pathway enzyme in HEK-KMO and HEK293 cells as determined by RT-qPCR