Figure 6

siRNA knockdown of the kynunenine pathway. (a) Graph showing cell death response indicated by LDH assay, n=2 for each knockdown conditions, the S.E.M. is indicated by error bars on the graph, data are from one independent experiment, knockdown of QPRT causes a significant increase (P=0.0077) in cell death as does knockdown of all four genes (P=0.0194). (b) Table showing the averaged knockdown efficiency for each gene in the cells