Figure 1 | Cell Death & Disease

Figure 1

From: Glutathione peroxidase 1 deficiency attenuates concanavalin A-induced hepatic injury by modulation of T-cell activation

Figure 1

Gpx1 deficiency protects from Con A-induced liver injury. (a) The expression of Gpx1 in the liver of WT and Gpx1 KO mice with Con A administration or without. (b) The expression of Gpx1 in the liver of WT and Gpx1 KO mice with Con A administration or without. n=8 per group; means±S.E.M., *P<0.05, WT mice without Con A administration versus WT mice with Con A administration, **P<0.05, WT mice without Con A administration versus KO mice without Con A administration, #P<0.05, WT mice with Con A administration versus Gpx1 KO mice with Con A administration. (c) Serum AST and ALT levels in WT and Gpx1 KO mice with Con A administration or without. n=8 per group; means±S.E.M., *P<0.05, WT mice without Con A administration versus WT mice with Con A administration, #P<0.05, WT mice with Con A administration versus Gpx1 KO mice with Con A administration. (d) Liver sections of WT and Gpx1 KO mice with Con A administration or without were stained with hematoxylin and eosin (H&E) (scale bars, 100 μm)

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