Figure 3
From: Loss of BRG1 induces CRC cell senescence by regulating p53/p21 pathway
KD of BRG1 increases the expression level of p53 and p21. (a and b) Western blot analysis for expression levels of BRG1, p21, and p16, and quantitative expression analyses of BRG1, p21, and p16 mRNA by quantitative real-time PCR (n=3, mean±S.D.) in SW48 and LoVo Sh-Con and HCT116 Sh-BRG1 cells. (c) Western blot detected the expression levels of BRG1 and p21 in multiple colon cancer cell lines. BRG/p21: the relative expression ratio between BRG1 and p21. *P<0.05; **P<0.01
