Figure 4
From: Salusin-β contributes to oxidative stress and inflammation in diabetic cardiomyopathy
Effects of knockdown of salusin-β with adenoviral vectors encoding salusin-β shRNA (Ad-Salusin-shRNA) on inflammation, oxidative stress and NFκB activation in neonatal rat cardiomyocytes. The cardiomyocytes were treated with both Ad-Salusin-shRNA (MOI=100) and HG (33.3 mM) for 24 h. Adenoviral vectors encoding scramble shRNA (Ad-Scr-shRNA) was used as a control of Ad-salusin-shRNA. (a) Effects of Ad-Salusin-shRNA on inflammation. (b) Effects of Ad-Salusin-shRNA on oxidative stress. (c) Effects of Ad-Salusin-shRNA on NFκB activation. Values are mean±S.E.M. *P<0.05 versus PBS; †P<0.05 versus Ad-Scr-shRNA. ‡P<0.05 versus Ctrl. n=6
