Figure 7 | Cell Death & Disease

Figure 7

From: Salusin-β contributes to oxidative stress and inflammation in diabetic cardiomyopathy

Figure 7

Effects of interrupting salusin-β on NFκB activation and oxidative stress in myocardium in rats with diabetes (DM). Intravenous injection of adenoviral vectors encoding salusin-β shRNA (Ad-Salusin-shRNA, 2.0 × 1010 plaque-forming units) or scramble shRNA (Ad-Scr-shRNA) were carried out and repeated for 2 weeks in rats. The measurements were made 4 weeks after the first adenovirus transfer. (a) NFκB activation. (b) Oxidative stress. (c) DHE staining for detecting ROS in myocardium. Values are mean±S.E.M. *P<0.05 versus Ctrl; †P<0.05 versus DM; ‡P<0.05 versus DM/Ad-Scr-shRNA. n=6

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