Table 1 Echocardiographic assessment of left ventricle dimensions and functions in rats

From: Salusin-β contributes to oxidative stress and inflammation in diabetic cardiomyopathy

 

Ctrl

DM

DM Scr-shRNA

DM Salusin- β -shRNA

LVIDs (mm)

4.66±0.20

5.71±0.18*

5.69±0.20*

5.14±0.17*†‡

LVIDd (mm)

8.36±0.30

8.60±0.22

8.35±0.27

8.52±0.18

IVSs (mm)

3.25±0.16

2.56±0.19*

2.51±0.18*

2.53±0.14*

IVSd (mm)

1.91±0.14

1.70±0.13

1.75±0.15

1.73±0.13

LVPWs (mm)

3.20±0.15

2.57±0.09*

2.49±0.13*

2.79±0.14*

LVPWd (mm)

1.96±0.06

1.74±0.08*

1.76±0.05*

1.83±0.07

LVVs (μl)

103±11

165±13*

157±11*

137±9*

LVVd (μl)

383±16

392±21

387±18

398±18

LVM (g)

1.11±0.10

0.95±0.11

0.92±0.08

0.91±0.07

LVM/BW (g/kg)

1.85±0.13

2.30±0.16*

2.26±0.11*

1.88±0.10†‡

EF (%)

73.1±2.6

57.9±2.2*

58.1±2.2*

65.6±1.7*†‡

FS (%)

44.0±1.3

33.6±1.8*

32.9±1.5*

38.5±1.8*†‡

  1. Abbreviations: BW, body weight; EF, ejection fraction; FS, fractional shorting; IVSs and IVSd, interventricular septum at end systole and diastole; LVIDs and LVIDd, left ventricular internal dimensions at end systole and diastole; LVPWs and LVPWd, left ventricular posterior wall dimensions at end systole and diastole; LVVs and LVVd, left ventricular volume at end systole and diastole; LVM, left ventricular mass Values are mean±S.E.M. *P<0.05 versus Ctrl; †P<0.05 versus DM; ‡P<0.05 versus DM/Scr-shRNA. n=6
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