Figure 2 | Cell Death & Disease

Figure 2

From: Deficiency of pigment epithelium-derived factor in nasopharyngeal carcinoma cells triggers the epithelial–mesenchymal transition and metastasis

Figure 2

Knockdown of endogenous PEDF expression in NPC cells induces EMT. (a) Cell morphology was evaluated by phase-contrast microscopy. (b) Representative micrographs of indicated cells grown on Matrigel for 8 days in 3D spheroid invasion assay. (c) The migration/invasion ability of indicated cells was evaluated by Transwell assay. (d) Expression of epithelial cell markers (E-cadherin, α-catenin) and mesenchymal cell markers (Vimentin, N-cadherin) in indicated cells were examined by WB. β-actin was used as a loading control. Bars correspond to mean±standard deviation (S.D.), *P<0.05

Back to article page