Figure 4 | Cell Death & Disease

Figure 4

From: Solute carrier family 12 member 5 promotes tumor invasion/metastasis of bladder urothelial carcinoma by enhancing NF-κB/MMP-7 signaling pathway

Figure 4

SLC12A5 regulated MMP-7 expression in BUC cells. (a) The nine genes, BRMS1, KISS1, PTEN, CXCR2, FGFR4, FLT4, MMP-3, MMP-7 and MAGT5, were examined >2-fold mRNA differential expression in SLC12A5-ShRNA -transfected T24 cells compared with that of T24-ShCtrl transfected by using a Human Tumor Metastasis RT2 Profiler PCR Array. (b) ShRNA-mediated SLC12A5 knockdown substantially upregulated PTEN expression and downregulated MMP-7 expression in T24 cells detected by western blot

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