Figure 6 | Cell Death & Disease

Figure 6

From: MiRNA199a-3p suppresses tumor growth, migration, invasion and angiogenesis in hepatocellular carcinoma by targeting VEGFA, VEGFR1, VEGFR2, HGF and MMP2

Figure 6

miR-199a-3p regulates extracellular matrix remodeling by targeting MMP2. (a) 3′-UTR-reporter-luciferase assay of MMP2 in HepG2 cells co-transfected with control vector and premiR-199a-3p. (b) MMP2 activity was determined by gelatin zymography in LX2, SNU449 and HepG2. (c) Western blot and (d) gelatin zymography of LX2 cells either transfected with premiR-199a-3p or control vector. **P<0.01

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